UP prides itself as the first university to offer veterinary medicine in the Philippines. The UP College of Vet Med was founded on 1908 as one of the original colleges of the UP System. It is the lone source of homegrown veterinary manpower in the country until the 1960s. Pagkatapos ng 1960, nagkaroon na rin ng Vet Med sa Gregorio Araneta University na ngayon ay De La Salle Araneta University; sinundan siya ng Central Luzon State University in Nueva Ecija sa tulong ng nag-iisang National Scientist for Veterinary Medicine na si late Dr. Teodulo Topacio, Jr.
